rh Adenoviruses



Adenoviruses cause disease by infecting epithelial cells in a variety of tissues and organs. Specific syndromes tend to be associated with particular adenovirus serotypes, of which there are nearly 50.

In immunocompetent patients they cause epidemics of pharyngoconjunctival fever (serotypes 3, 7), keratoconjunctivitis (serotypes 8, 19) and lower respiratory infection (in military recruits). They also cause endemic upper respiratory tract infection (serotypes 1, 2, 5), a small proportion of pneumonia (about 10% in children), sporadic gastroenteritis (serotypes 40, 41) and haemorrhagic cystitis (serotypes 7, 11, 21, 35).

In immunosuppressed patients they may cause disseminated infection involving the lung, liver, gut and urinary tract. Haemorrhagic cystitis and pneumonia are the most frequent adenovirus syndromes in transplant recipients. There is no effective antiviral therapy and no vaccines available for general use.

Concepts of infection
Major manifestations of infection
Principles of management of infection
Diseases due to viruses
DNA viruses
Diseases due to chlamydiae
Diseases due to rickettsiae
Diseases due to bacteria
  • Streptococcal infections
  • Staphylococcal infections
  • Corynebacterial infections
  • Bacillus infections
  • Bordetella infections
  • Salmonella infections
  • Food poisoning
  • Dysentery
  • Other true bacterial infections
  • Mycobacterial infections
Diseases due to spirochaetes
  • Leptospira infections
  • Borrelia infections
  • Treponema infections
Diseases due to fungi (mycoses)
  • Cutaneous fungal infections
  • Subcutaneous fungal infections
  • Systemic fungal infections
Diseases due to protozoa
Diseases due to helminths
  • Trematode (fluke) infections
  • Cestode (tapeworm) infections
  • Nematode (roundworm) infections
  • Zoonotic helminth infections
Diseases due to arthropods
Sexually transmitted diseases
  • Sexually transmitted bacterial diseases
  • Sexually transmitted viral diseases
  • Miscellaneous conditions